Available technologies

Sensitive multiplex nanopore protein screening using aptamer-modified DNA carriers

Reference number: 8194

DNA blue strand

A flexible and selective approach to nanopore protein screening for accurate detection of multiple analytes. The invention utilises single-stranded oligonucleotide aptamers conjugated to double stranded DNA (dsDNA) molecular carrier. In the invention, aptamer sequences are extended to hybridise to a complementary DNA carrier, together forming a specific detection probe. Advantageously, the carrier is generic and can be used in all situations, while the aptamer is specific to the target protein.

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contact

Marcio Siqueira

Industry Partnerships and Commercialisation Senior Executive, Natural Sciences

m.siqueira@imperial.ac.uk

+44 (0)207 594 5505

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