A comprehensive nanoparticle analysis platform based on Raman spectroscopy providing simultaneous size, composition and functionalisation analysis as well as allowing monitoring of dynamic reactions occurring the surface of individual particles.
A novel multi-laminar and anisotropic osteochondral scaffold has been developed and preliminary in vivo data obtained. This scaffold mimics the natural structure of articular cartilage, which is a highly organized, fibre-reinforced tissue with specific mechanical and biological properties.
The present invention relates to a novel DNA delivery vector for targeted gene therapy, medical imaging and vaccination with increased efficacy over existing technologies. The platform comprises a phagemid hybrid with phage and recombinant adeno-associated virus (AAV) components.
A novel viral delivery vector with scope for more cost-effective commercial production over existing technologies. The platform comprises a phagemid hybrid with recombinant adeno-associated virus (AAV) components.
A new solution to prevent seismic waves and ground vibration from harming buildings and structures
GBP6 and BATF2 have been identified as novel, highly specific and sensitive biomarkers for TB and determination of their expression levels in peripheral blood can distinguish active TB from latent TB or uninfected individuals.
In-patient ratios of two protein biomarkers found in blood serum (CSF1R for SA and S100A8/A9 for TB) can provide excellent differential diagnosis of Sarcoidosis versus Tuberculosis, with potential for development into a low-cost, reliable ELISA-based diagnostic test.
Researchers at Imperial College London have developed two novel modifications of bacteriophages to significantly improve their efficacy as vectors for targeted gene therapy, and exploit their advantages over eukaryotic viral vectors.
Suite of microRNAs for predicting cervical shortening and preterm birth that can be measured from blood samples taken in early pregnancy (from gestation week 12 onwards).
Novel truncated fragments of von Willebrand factor (VWF) engineered by a team at Imperial College London.